Diafiltration
DF
Diafiltration (DF) supplements solution during filtration to wash out or replace small components surrounding retained substances.
In context
It changes surrounding solution composition while retaining large molecules. Its purpose differs from simple volume reduction.
Example
Retaining a hypothetical protein on a membrane while reducing liquid volume can concentrate it. Changing surrounding solution components differs in purpose from simply reducing volume.
Key distinction
UF and DF may be combined, but distinguish concentration adjustment from solution composition changes.
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